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Biomedicine Advances welcomes submissions in the following categories:

Editorials

 Thoughtful discussions or critiques of published articles or relevant issues.

Editorials, authored by the Editor, Associate Editors, or invited experts, provide commentary on general interest to the journal’s readership and align with the publication's focus. Submissions for editorials are by invitation only. Manuscripts should not exceed 1,000 words and may include up to 10 references.

Original Research Articles

Comprehensive studies presenting new findings based on the journal’s aim and scope.

Research articles should present original primary research or introduce new experimental or computational methods, tests, or procedures.

In alignment with the International Committee of Medical Journal Editors (ICMJE), Biomedicine Advances mandates the registration of all trials in a publicly accessible registry approved by the ICMJE as a prerequisite for publication consideration.

Manuscripts detailing the results of clinical trials must adhere to the CONSORT 2010 guidelines. Authors of randomized controlled trials must submit a completed CONSORT checklist, available at https://www.consort-spirit.org.

Full-length articles should be structured as follows, with each section organized and prepared according to the guidelines:

  • Title Page: the title page should:
  • Provide a descriptive title that includes the study design when applicable (e.g., "A versus B in the Treatment of C: A Randomized Controlled Trial," "X as a Risk Factor for Y: A Case-Control Study," or "Impact of Factor X on Subject Y: A Systematic Review") or, for non-research or non-clinical studies, a clear description of the article's focus.
  • Include the full names and institutional affiliations of all authors.
  • If applicable, list a collaboration group as an author specifying the group name. To ensure the individual names of group members are searchable in PubMed records, include this information in the “Acknowledgements” section, adhering to the journal’s guidelines.
  • Note that Large Language Models (LLMs), such as ChatGPT, do not meet authorship criteria, as authorship requires accountability that cannot be applied to LLMs. If an LLM is used, its contribution should be documented in the Methods section or an alternative appropriate section of the manuscript.
  • Identify the corresponding author.
  • Summary: A structured abstract of no more than 250 words, including the following subsections: Background, Methods, Findings, and Conclusion.
  • Trial Registration: The journal requires authors to register the clinical trial discussed in the manuscript in a public trial registry and provide the trial registration number at the end of the abstract.
  • Keywords: Relevant keywords to aid indexing and discovery.
  • Introduction: Background and objectives of the study.
  • Methods: Detailed methodology, including statistical considerations.
  • Results: The study's findings are presented clearly and concisely.
  • Discussion: Interpretation and implications of the results.
  • Conclusion: Summary of key findings and their relevance.
  • Acknowledgements: Recognition of contributions that do not warrant authorship.
  • Authors' Contributions: To ensure transparency, authors must include a statement detailing their contributions to the paper in the manuscript file. Contributions should be specified using the following roles: Conceptualization, Methodology, Validation, Formal Analysis, Investigation, Resources, Data Curation, Writing—Original Draft Preparation, Writing—Review and Editing, Visualization, Supervision, Project Administration, and Funding Acquisition. Authors should indicate their contributions by listing their full names.
  • Competing Interests: Disclosure of any potential conflicts of interest.
  • Ethical Approval: Confirmation of compliance with ethical standards.
  • Funding: Details of funding sources supporting the research.
  • References: Complete and accurate citations following the journal's referencing style.
  • Figure and Table Legends: Clear legends for all figures and tables included in the manuscript.

Each section should be well-organized and adhere to the journal's formatting requirements.

Review Articles

Summaries of current knowledge, addressing significant topics in the field.

The journal accepts narrative reviews, systematic reviews, and meta-analyses focused on clinically relevant biomedical research. Submissions should be authored by recognized experts in the field, with a preference given to systematic reviews and meta-analyses.

For systematic reviews submitted to Biomedicine Advances, authors must include a completed PRISMA checklist and flow diagram. The flow diagram must be incorporated into the main text, while the checklist should be submitted as a supplementary file. Both elements should be cited within the manuscript. The editor will return submissions lacking these components and request their completion. Templates for the checklist and flow diagram are available for download. (https://www.prisma-statement.org/prisma-2020-checklist)

It is acknowledged that certain systematic reviews may not fully adhere to all items on the PRISMA checklist. The checklist is not intended as a criterion for assessing the publication eligibility of manuscripts but rather serves as a tool to help authors present their findings, comprehensively, and transparently for reviewers and readers. Adhering to the PRISMA guidelines, completing the checklist, and developing a flow diagram are recommended practices that enhance reporting quality and streamline the peer-review process.

Review articles must include an unstructured summary, keywords, an introduction, the main text organized with appropriate subheadings, a discussion, a conclusion, acknowledgments, authors' contributions, competing interests, funding, references, and legends for tables and figures.

All tables and figures must be referenced in the manuscript under the sequence of citations in the text.

Case Reports

Detailed analyses of rare or unique clinical cases with educational or scientific relevance.

Biomedicine Advances invites well-documented case reports that encompass the following:

  • Rare or unreported side effects or adverse interactions involving medications.
  • Unusual or unexpected presentations of diseases.
  • Novel associations or variations in disease processes.
  • Presentations, diagnoses, and management of emerging diseases.
  • Unexpected connections between diseases or symptoms.
  • Unexpected events during patient observation or treatment.
  • Findings that provide new insights into the pathogenesis of diseases or adverse effects.

Submitted case reports should contribute to medical knowledge, offer educational value, or underscore the need for changes in clinical practice, diagnostics, or prognostics. The journal does not accept case reports on preventive or therapeutic interventions, as these typically require more robust evidence. Reports on topics already well-documented or cases similar to those previously published will also not be considered.

Authors are encouraged to highlight the rarity or uniqueness of their case and its scientific or educational significance in a cover letter accompanying the manuscript submission. All submissions undergo an initial evaluation by the Editors and, if considered appropriate, are subsequently forwarded for peer review.

Case reports should include relevant findings from the patient’s history, examination, and investigations, along with clinical photographs (where applicable). An up-to-date review of previous cases in the field is required.

Written, signed consent to publish must be obtained from the patient(s) or their guardian(s) before submission. The manuscript must include a statement confirming this consent in the "Consent to Publish" section, as outlined in the journal's editorial policies.

Short Communications

Concise reports of preliminary or novel findings.

Short communications are original studies presenting findings in any area of biomedicine research that are less extensive than a standard research article. These manuscripts should be structured similarly to full-length articles but must not exceed 2,000 words, including tables and figures, and should contain no more than 25 references. There should be a maximum of four figures and/or tables. Any additional display items can be published online as supplemental information. For short articles, the results and discussion sections may be merged.

Commentaries

 Commentaries provide concise and well-structured perspectives, concerns, or viewpoints on significant and timely topics relevant to the journal's audience.

A Commentary article typically falls into one of two categories:

The first type discusses a recently published or upcoming article or trial that is noteworthy enough to merit further commentary or clarification. Rather than covering an entire field, it focuses on specific issues within a subject area, explains the article’s implications, and provides context. Opinions are encouraged, provided they are backed by factual evidence.

The second type is more editorial in nature and addresses an issue relevant to the journal’s scope. Examples include discussions on the impact of new technology on research and treatment or changes in peer review and grant application procedures and their effects on research. This type of Comment is published less frequently.

Manuscripts should be limited to 800 words and organized with a title, an unstructured summary (should not exceed 50 words), keywords, main text, conclusions, and references. Each commentary may include up to three authors, a maximum of six references, and one figure or table.

Corrections

 Biomedicine Advances issues corrections when, after editorial review, all of the following criteria are met:

  • The error affects the core content or interpretation of the article.

  • The main findings and conclusions of the article remain valid.

  • There are no concerns regarding the integrity or trustworthiness of the research.

Additionally, Biomedicine Advances may publish corrections to amend significant metadata errors or omissions—such as author names, conflict of interest disclosures, or funding information—or to include supplementary datasets or details required to meet the journal’s research reporting standards.

General Considerations

Text

  • Manuscripts should be submitted as a Word document.
  • Use a standard, simple font, such as 10-point Times New Roman, for the main text.
  • Apply italics for emphasis.
  • Enable automatic page numbering instead of adding numbers manually.
  • Avoid using field functions.
  • Use tab stops or formatting commands for indentations rather than the space bar.
  • Create tables using the table function rather than spreadsheets.
  • Utilize the equation editor or MathType for inserting equations.
  • Save the file in .docx format (Word 2007 or later) or .doc format (for older Word versions).

Tables

Tables should be placed within the main text immediately after their first mention, with a relevant caption positioned above them. Captions should not be part of the table itself (i.e., not a row or column).

  • Ensure that tables are properly formatted with real rows and columns rather than using tabs, spaces, or line breaks for alignment.
  • If presenting multi-part tables with different column structures or multiple footnotes, organize them as separate tables.
  • Tables should be simple and free of colors, shading, or graphics.
  • Cite tables in numerical order as they first appear in the manuscript.
  • Define symbols and abbreviations immediately below the table, followed by a brief but essential description.

Figures

Figures and illustrations must be cited in numerical order within the main text, with relevant captions placed separately and not embedded in the figures.

Acceptable file formats:

  • Photography/Microscopy: Adobe Portable Document Format (PDF, TIFF)
  • Illustrations/Diagrams: Encapsulated PostScript (EPS)
  • Chembioffice Files: Enhanced Metafile (EMF)
  • Matlab Figures: PDF
  • MathType Software: Windows Metafile (WMF)
  • Excel Charts: Submit in their original editable format (Word), not as static images.

Editors may request access to underlying data (e.g., Office, SPSS, or other line-art images).

Image resolution requirements:

  • Color figures: At least 300 dpi
  • Greyscale images: At least 600 dpi
  • Line art: At least 1200 dpi
  • Histograms should be in a simple, two-dimensional format without background grids.
  • Remove or black out any patient/hospital identifiers in medical images (e.g., X-rays, MRI scans).
  • If patient photographs are included, they should be non-identifiable; do not use black bars to obscure identities.
  • Lettering in figures (e.g., axis labels) should be in lowercase, with only the first letter capitalized and no full stop. Use a sans-serif font, preferably Arial.
  • Multi-panel figures (e.g., with labeled parts a, b, c, d) should be submitted as a grouped file.

Acceptable Digital Formats

  • Vector-Based Formats: CorelDraw, Adobe Illustrator, and unlocked PDFs created from a vector program.
  • Microsoft Office Files: PowerPoint, Excel, and Word are acceptable, provided that graphs are not inserted as rasterized (pixel-based) images.

Unacceptable File Formats:

  • Canvas, DeltaGraph, TeX, and SigmaPlot are not accepted. These files must be converted to PDF, EPS, or PostScript format before submission.

Formula

  • Equations must be created using MathType (Download: MathType Software).
  • Do not use graphical objects to create equations. Ensure all equations remain editable.
  • Equations composed using Microsoft Word’s built-in equation editor will become unusable during typesetting. To prevent this, re-enter all equations using MathType.
  • Long equations should be set apart from the main text and numbered sequentially.
  • Refer to equations in the text using their assigned numbers (e.g., "Eq. 1" or "Eqs. 2 and 3").

References

References should be arranged as a simple list at the end of the manuscript, following the journal's EndNote style

  • Authors are responsible for ensuring the accuracy of all cited references before submission.
  • Each reference number should correspond to only one publication (no multiple sources under one number).
  • Acceptable references include published conference abstracts, numbered patents, and preprints on recognized servers. However, references should not include text, grant details, or acknowledgments.

Citing in the Text

  • References should be cited sequentially in the text using the Vancouver numbering style, appearing as superscripted numbers placed after the nearest punctuation mark (e.g., as reported by Myo and colleagues. 10).
  • When citing two references, use a comma without a space (e.g., ...previous studies have shown this effect. 2, 3).
  • For three or more consecutive references, use a dash to indicate a range (e.g., ...consistent with previous research. 7-10).
  • References in tables, figures, and panels should follow numerical order based on where they are first cited in the text.
  • Do not enclose reference numbers in parentheses (e.g., incorrect: (14), correct: 14).
  • Manuscripts with references not cited in order may be returned for revision before editorial assessment.
  • The reference list should only include published or in-press works. Personal communications or unpublished data should be cited in parentheses within the text, including the source’s name and year (e.g., (J. Smith, personal communication, 2023)). Authors should obtain permission from the source before citing unpublished data.